Medications can be categorized as “yellow” for a multitude of reasons. “Yellow” does not always mean that the medication should not be used in that individual. Rather it means that there are special considerations/instructions for that individual if they are prescribed that medication. For example, the person may need an alternate dose (vs. the standard dose that is usually prescribed), or they may need to be on the look-out for certain side effects or drug interactions that may occur based on gene variants they carry that would not typically be seen in most people.
If a medication has been labelled “yellow” due to predicted lack of effectiveness (predicted lack of response), but no safety risks have been identified, and you feel the medication is working well for you, it is generally not recommended that you discontinue the medication
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